What is Mesima Mushroom?

Vitality, long life, and eternal youth. These are some reasons why Chinese emperors and Japanese royalty chose the mesima mushroom. Also known as meshimakobu, son gen, and sang-hwang, this mushroom is a superior oriental herbal medicine. 

Biologically known as Phellinus linteus, this orange-colored mushroom grows on the wood of different trees, mainly mulberry. Its fruiting body is woody, dark, and shaped like a large hoof. 

But while it may look appetizing, it has a distinct bitter taste. That’s why supplements such as Host Defense Mesima capsules are comparatively more popular. You only need to pop two pills a day to enjoy all the benefits this medicinal mushroom has to offer. 

Mesima Mushroom Health Benefits

Mesima mushrooms are rich in micronutrients like beta-glucans, lectin, polysaccharides, and inoscavin. These promote overall health while adding years to your life. 

To be more specific, here are the main benefits you reap by adding mesima mushrooms to your daily diet. 

Immune System

The meshimakobu mushroom can act as a turbo shot for your immune system. In fact, studies show that it has potent immunomodulating effects and can be used to enhance immunity. 

As a medicinal mushroom, mesima contains beta-glucans. These are potent polysaccharides that fight inflammation and balance the immune system. By attaching to the receptor sites of immune cells, they activate them and improve their response to ‘foreign’ cells. 

The mushroom also contains powerful antioxidants that can prevent DNA damage and even repair it. This, in turn, prevents disease as well as improves healing. 

Moreover, Phellinus linteus is beneficial for gut health. It heals the gastrointestinal tract and strengthens it against bacterial infections. 

Wondering how these two relate? Well, the gut and immune systems rely on one another to ensure a healthy body. 


While a hyperactive immune system may be triggering allergy symptoms, chronic inflammation can also be a culprit. Thankfully, Phellinus linteus offers a natural solution to combating inflammation. Its bioactive compounds and antioxidants give the mushroom its anti-inflammatory qualities. 

Therefore, the mushroom may block allergy symptoms by balancing the immune system and reducing inflammation.  

Another way the mushroom extract can help with allergies is by suppressing the release of histamine. This chemical causes many of the symptoms of allergies as it signals to cells that the body is under attack. 

As a natural antihistamine, the mushroom may also relieve asthma caused by allergies. It can further be used against skin ailments caused by allergies such as atopic dermatitis. 

Women’s Health

The mesima mushroom is increasingly gaining popularity in the Western world for its numerous benefits for women. 

The mushroom delivers blood staunching abilities. First off, it helps control excessive bleeding during periods. It’s proven to be especially beneficial for women experiencing menorrhagia, a condition causing heavy bleeding during periods. And studies are underway to determine if it can control hemophilia. 

The mesima mushroom is also being studied for its effects on breast health. Its rich polysaccharide content and anti-inflammatory properties can protect breast tissue and maintain healthy breast cells. 

Mesima Mushroom for Fertility

One of the most significant benefits the mesima mushroom offers women is aiding them to conceive. This is possible by lowering the levels of cytokine and NK cells in the body. 

An increase in cytokines results in the imbalance of sex hormones critical for conception. If the issue persists, pro-inflammatory interleukins will impact fertility. 

Similarly, NK cells can impact fertility. Uterine NK can interfere with the implantation and development of eggs. They may also lead to miscarriages as they affect early placental development.  

By controlling both, women can improve their fertility and increase their chances of carrying full term. 

Mesima Mushroom for Cancer

The mesima mushroom is constantly making headlines in cancer research journals. The mushroom’s micronutrients have been quite helpful in fighting against different types of cancer. 

The mushroom’s polysaccharides sensitize colon cancer cells. That way, even a lower dose of chemotherapy can be effective against cancer cells. As a result, there are fewer harmful side effects and almost no damage to non-cancerous colon cells. 

An animal study further explored the effects of a water extract on human prostate cancer cells. Researchers noted that the extract prevented the growth of new tumors while slowing down existing ones. Therefore, it may help prevent the remission of prostate cancer in patients. 

A growing number of studies indicate Phellinus linteus can help against breast cancer. The mushroom can prevent human breast cancer cells from evolving successfully and invading the body. 

In addition to these benefits, the mushroom supports immune function and increases the effectiveness of anti-cancer drugs. Therefore, it can complement patients’ therapies to give them a better chance at recovering. 

Mesima Mushroom Side Effects

Mesima mushrooms have been used for over 5,000 years because of their limited side effects. However, they may not be recommended for individuals allergic to mushrooms or who have extremely low blood pressure. 

There’s also limited information on their safety for pregnant or breastfeeding women. Therefore, you may want to avoid using them to be safe. 

In addition, some early studies suggest that sang-hwang may worsen the autoimmune disease by increasing immune function. Therefore, individuals with multiple sclerosis, rheumatoid arthritis, and other autoimmune disorders should only use it after consulting an expert. 

Other studies also indicate the mushroom may enlarge the prostate. Therefore, men with benign prostatic hyperplasia should avoid using it altogether.  

These issues aside, there’s nothing to stop you from adding mesima mushroom to your diet. Especially as it has no known interactions with medications or known supplements. 

Phellinus Linteus Dosage

Too much or too little of the mesima mushroom may result in poor effects or none at all. Besides, some factors impact the dose, such as the product’s type, age, and overall health. 

Ideally, you need to adhere to the recommended dosage of the products you purchase. This will differ based on the type of product you purchase. 

For example, powders like Myriad Mycology Mesima Sang-Huang recommend 1 tsp twice daily. Meanwhile, you’ll need to take 1-3 capsules a day. 

Is Black Hoof the Same as Mesima Mushroom? 

Good catch there. Yes, the mesima mushroom is the same as the black hoof mushroom. The latter is the name commonly used for it in the United States. And as you probably have guessed, the name is the result of the mushroom’s hoof-like shape and coloring. 

The Bottom Line 

There’s a reason the mesima mushroom has withstood the test of time. It’s a potent medicinal mushroom that can improve the quality of life for many individuals burdened by chronic disease. 

And not just for the health problems you just read about. There’s growing evidence that mesima can also help with diabetes, infections, and aging-related issues. 

Unfortunately, the research proving these benefits is currently limited. So, you need to consult your physician before using the mushroom as a stand-alone treatment. However, that shouldn’t stop you from using it to complement your treatments or as a supplement to improve your overall health. 

Just remember to choose pure, non-GMO products with zero additives. That way, you can get all the benefits you read about without any chemicals impacting the results. 

So, when will you be adding the black hoof mushroom to your daily diet?