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Best Nootropic Stack for Anxiety


Unfortunately, anxiety and anxiety disorders affect as many as 30% of adults at some point throughout their lives. In fact, according to official numbers, up to 15,000,000 adults, or roughly 7.1% of the United States adult population, are affected by some form of social anxiety disorder.

These are some really sobering numbers, and it just goes to show how many people are affected by mental health disorders. Many people might try to resort to prescription medications to care for their mental health issues, which is certainly a reasonable route.

However, prescription medications aren't for everybody, giving people limited options. That said, nootropic supplements are one option at your disposal, and they may go quite a long way in helping control your anxiety.

For those who don't know what nootropics are, these are substances that are said to help improve overall mental performance and cognitive abilities. This begs the question of what nootropics are best for anxiety. This is what we are here to help you with today: finding the best nootropic stack for anxiety.

Key Takeaways

  • Anxiety may be caused by a variety of factors but is usually associated with hormonal and chemical imbalances.
  • There are various nootropic substances that may be able to help regulate neurotransmitters and chemicals in the brain, therefore reducing symptoms associated with anxiety.
  • Nootropics can also be used for procrastinationfocus, and sleep!

What Causes Anxiety?

Before we can start talking about the best substances to help get rid of your anxiety, it's important to know why you have anxiety to begin with. 

For many people, anxiety may be circumstantial in nature. For instance, anxiety may be caused by a traumatic past event in your life that you now keep reliving.

Anxiety may also be caused by the thought of a future event. Many people have social anxieties that make them feel very nervous when they have to attend various events with lots of people. Both the thought of past traumatic events and the idea of future events, whether some people might find them traumatic or not, could all lead to anxiety.

However, for the most part, the initial cause of your anxiety is irrelevant when you consider that most forms of anxiety are likely caused by imbalances of the various neurochemicals in your brain. 

Neurochemicals may also be referred to as neurotransmitters, and they are primarily responsible for communicating between various parts of your body and brain.

Some of the most important neurotransmitters in your brain and body include GABA, serotonin, dopamine, acetylcholine, norepinephrine, and glutamate.

If the levels of any of these neurotransmitters are off, usually associated with being too low, then you may suffer from anxiety, as well as possibly depression, increased stress levels, mood swings, and more. Therefore, it would appear that controlling the levels of these various neurotransmitters is the name of the game as far as reducing anxiety is concerned.

What are the Symptoms of Anxiety?

If you're unsure whether or not you have anxiety, there are quite a few common symptoms that you may experience, including the following:

  • Restlessness
  • The inability to concentrate
  • Insomnia and difficulty sleeping
  • Excessive and unreasonable worrying.
  • Palpitations and increased heart rate.
  • Shortness of breath.
  • Chest pains.
  • An inability to concentrate and focus.
  • Hot flashes.
  • Sweating.
  • Fatigue.
  • Trembling.
  • Feelings of impending doom and terror.

How Can Nootropics Help Anxiety?

Although many nootropic and adaptogenic substances may help improve your cognitive functions, such as your ability to reason, remember, solve problems, and more, they can also be beneficial in terms of anxiety. Nootropics often come in the form of mushrooms!

Are Nootropics Good for Anxiety?

Indeed, some nootropic substances can be good for anxiety. What it all comes down to is that certain substances considered nootropics can regulate levels of various neurotransmitters in our brains, such as the ones we discussed above.  

Dopamine, serotonin, acetylcholine, GABA, and cortisol are some of the most important ones.

As you'll see further below, all of the nootropics for anxiety that we list are, in one way or another, able to help regulate these neurotransmitters.

Can Nootropics Cause Anxiety?

Although it is much more common for a nootropic substance to decrease anxiety than to increase it, strictly speaking, it is possible. 

Remember that everybody may react differently to various substances, so it's always best to consult the health care practitioner before starting any new regimen.

Best Nootropics for Anxiety

Now that we know that nootropics may help reduce your anxiety levels let's look at some of the best ones out there.


This is a specific amino acid most commonly found in green tea. There are many studies out there that suggest that L-theanine may be able to reduce both anxiety and stress levels. 

Here is another study that suggests that L-theanine may reduce symptoms related to stress and anxiety within as little as just one hour after consuming it. It is assumed that stress and anxiety levels are alleviated thanks to this substance due to its ability to lower cortisol levels.

Gotu Kola

Guto Kola is a herb used in many Asian cultures, particularly in India, China, and Indonesia. This is a so-called adaptogenic herb that is known for having a variety of health benefits. 

One such benefit is its ability to increase cognitive functions like memory, learning, and problem-solving. This adaptogenic herb is also shown to be effective at reducing symptoms related to stress and anxiety in people, as suggested by this study.

Rhodiola Rosea

Rhodiola Rosea is yet another fantastic adaptogenic herb that is shown to have many different benefits for both the brain and body. More than anything else, it is shown to help reduce symptoms related to stress and anxiety.

It may help reduce instances of anger and confusion and even reduce mood swings. Here's another study that suggests this substance may effectively reduce symptoms related to general anxiety disorder.

Bacopa Monnieri

As far as traditional Indian medicine is concerned, bacopa monnieri is one of the most popular ones of all. 

This adaptogenic substance is often used in Asia, Africa, Australia, and North America. It may enhance memory, improve focus, allow for clear thinking, and enhance general cognitive function.

There are also studies that suggest that it can be effective at improving the speed of visual processing as well as your rate of learning. 

Furthermore, some studies show that it may be used to help decrease symptoms associated with anxiety. This substance has the ability to lower cortisol levels, therefore helping to reduce both stress and anxiety.


Ashwagandha, which comes from a root, is yet another fantastic substance that may be able to reduce symptoms often related to anxiety. 

According to this one piece of research from 2019, ashwagandha is able to affect hypothalamic pituitary adrenal function, which determines how different parts of your brain interact with each other.

Ashwagandha is also known as an adaptogen, which means that it helps your body adapt to various levels of stress. 

This study suggests that this substance shows very real potential to be used as an alternative treatment to regular medicines for anxiety.

Valerian Root

We then have valerian root, yet another substance that is shown to help combat symptoms associated with anxiety. Although it is not 100% sure how this works, it is thought that valerian root helps to increase GABA levels in your brain.

GABA is known to regulate nerve cells and also has a common effect. This substance is often directly linked to stress and anxiety levels. Valerian root is most often made into teas, although it can also be turned into powder.

B Vitamins

We then have the B vitamins, specifically vitamins B9 and B12. These are both believed to be effective at treating symptoms related to anxiety. 

When vitamins B9 and B12 are taken together, they are able to help metabolize serotonin better. Serotonin is one of the most known important transmitters in your body that affects mood regulation and may lead to increased or decreased levels of anxiety.


As we've covered above, GABA, or gamma-aminobutyric acid, also plays an important role in mood regulation. It is believed that higher levels of GABA can help to induce a calming effect on the mind, therefore ultimately reducing symptoms related to anxiety.


5-HTP is a specific type of dietary supplement that is known for raising serotonin levels. Increased serotonin levels are associated with better moods, euphoria, happiness, and a better mood.

Phosphatidylserine (PS)

This is a special type of phospholipid compound comprising a small amount of fats found in the human brain. 

It promotes the production of various neurotransmitters, with acetylcholine and dopamine being two of the most important ones. 

Both acetylcholine and dopamine are associated with decreased symptoms of anxiety and stress. It may also be able to reduce the production of cortisol, the stress hormone.

Where to Find Nootropics for Anxiety

If you are looking for nootropics for anxiety, we recommend checking out TUNE IN, a super simple drink mix that contains a wide variety of nootropic ingredients, all of which have the potential to help you manage your anxious mind, while also increasing your cognitive abilities and energy levels.

Specifically, it has the potential to increase levels of dopamine, acetylcholine, and epinephrine, all of which are in their own ways related to anxiety. 

TUNE IN is available in Pink Lemonade and Tropical Punch flavors, and you just have to mix it in with water or your favorite drink and consume it once per day.

Final Thoughts

The bottom line here is that you don't need expensive prescriptions to help reduce anxiety levels, because there are plenty of nootropic and adaptive genic substances out there that have the potential to do the same. If you want to reach the maximum possible benefits of various nootropics, we certainly recommend checking out TUNE IN.

Nootropics for Anxiety: FAQs

What is the Strongest Nootropic for Anxiety?

Some of the strongest nootropics for anxiety include ashwagandha and Rhodiola Rosea.

Are Nootropics Good for Anxiety?

For many people, nootropics are good for anxiety.

What Supplements Stack with Anxiety?

B Vitamins, GABA, 5-HTP, ashwagandha, Rhodiola Rosea, bacopa monnieri, and many others can all stack together to help reduce levels of anxiety.

VYU Blog Disclaimer

The information provided on the VYU blog is intended solely for informational and entertainment purposes. It should not be used as a substitute for professional medical advice, diagnosis, or treatment.

Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment and before undertaking a new healthcare regimen. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

For more information, check out our FAQs and contact page.

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